# \#modeling

**URL:** https://discourse.scverse.org/tag/modeling/25.md

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## [totalVI, peakVI, multiVI with scRNA-seq and scATAC-seq data](https://discourse.scverse.org/t/totalvi-peakvi-multivi-with-scrna-seq-and-scatac-seq-data/296)

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**Author:** [@Z\_Huang](https://discourse.scverse.org/u/Z_Huang)\
**Replies:** 3\
**Last updated:** [March 9, 2023, 5:53pm UTC](https://discourse.scverse.org/t/totalvi-peakvi-multivi-with-scrna-seq-and-scatac-seq-data/296 "2023-03-09T17:53:07Z")

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Hi community, I am new to scvi-tools and I went through all of the tutorials. I learned peakVI consumes scATAC-seq data for DNA analysis; totalVI consumes CITE-seq data for RNA and protein analysis. Here is my question…

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## [Novel Model for Clustering Developmental Data (starting from scANVI)](https://discourse.scverse.org/t/novel-model-for-clustering-developmental-data-starting-from-scanvi/253)

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**Author:** [@mtvector](https://discourse.scverse.org/u/mtvector)\
**Replies:** 1\
**Last updated:** [October 10, 2022, 5:48pm UTC](https://discourse.scverse.org/t/novel-model-for-clustering-developmental-data-starting-from-scanvi/253 "2022-10-10T17:48:16Z")

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Hi there, amazing work on developing such a useful model and spinning it into a cool suite of tools. So I’ve been working on a generative model to cluster developmental data. The idea is essentially to assume that cell …

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## [Batch Integration Parameter Tuning](https://discourse.scverse.org/t/batch-integration-parameter-tuning/315)

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**Author:** [@abbass2](https://discourse.scverse.org/u/abbass2)\
**Replies:** 1\
**Last updated:** [March 2, 2022, 11:28pm UTC](https://discourse.scverse.org/t/batch-integration-parameter-tuning/315 "2022-03-02T23:28:48Z")

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Hello, Great tool, thanks for all your efforts…couple questions below. I am integrating ~500K cells from \> 40 donors, and I am interested in parameter tuning for the model. I’m new to neural networks, but it seems like…

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## [Model complexity selection](https://discourse.scverse.org/t/model-complexity-selection/139)

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**Author:** [@Anatoly\_Buchin](https://discourse.scverse.org/u/Anatoly_Buchin)\
**Replies:** 5\
**Last updated:** [February 10, 2022, 4:28am UTC](https://discourse.scverse.org/t/model-complexity-selection/139 "2022-02-10T04:28:18Z")

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Hi everybody, I am currently running the scvi-tools to perform batch correction and dimensionality reduction of the dataset consisting of multiple patients. I am not sure about the complexity of the model that has been …

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## [Models for handling hundreds of batches](https://discourse.scverse.org/t/models-for-handling-hundreds-of-batches/24)

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**Author:** [@munfred](https://discourse.scverse.org/u/munfred)\
**Replies:** 4\
**Last updated:** [September 8, 2021, 9:05am UTC](https://discourse.scverse.org/t/models-for-handling-hundreds-of-batches/24 "2021-09-08T09:05:13Z")

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Hello, I routinely train scVI models with up to 30 batches without a hitch. In my case I’m integrating all publicly available C. elegans data, which will continue to grow and is likely to reach hundreds of batches within…