Regressing out variables in pearson residual normalization


I was looking into normalizing my single cell data using the Pearson Residual method in the experimental API. However, previously I regressed out mitochondrial & cell cycle differences in Seurat with SCTransform (it was a paramter within SCTransform). I was wondering in the case of Pearson Residuals, is it possible to perform the regression on the normalized Pearson Residuals?

Thank you!