Hi there,
I was hoping to identify (1) cells that are more likely able to interact/bind to certain proteins/genes and (2) cells that are more likely to bind to other cells, and (3) ultimately leveraging network inferences to put these interactions in established disease or signaling pathways.
Anyone know of a tool or resources to do this for example to identify cell-protein interaction by comparing a protein/gene sequence of interest (and perhaps their structure predicted by alpha fold and other biophysiochemical properties) to the human proteome to identify potential interaction?
Or, by performing receptor-ligand interactions between 2 transcriptome/multiomics to identify cell-cell interaction?
Thank you so much!