How to best integrate scRNA-seq with transcription factor expression measured by fluorescent signals

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Hi,

I have two datasets from the same tissue: one is scRNA-seq matrix (86000 cells*20000 genes), another one is 620 TF expression measured by DAPI fluorescent signals (fractional values), (600 cells * 620 TFs), they overlap with 609 TFs (genes). Is there a good way to integrate these two datasets? Thanks!